Turning Off One Gene Blocks PTSD in Mice: StudyThis is from 2008
December 1, 2015
A new study on older mice finds that fear responses can permanently disappear when this gene is blocked
A new study on mice, published Tuesday in the journal Molecular Psychiatry, could help pave the way for a more effective way to treat post traumatic stress disorder (PTSD) in humans.
Using an animal model for human PTSD, in which researchers conditioned mice to feel fear and then attempted to reverse it, the scientists found that blocking a single gene in mice could turn off their chronic fear response.
In the study, the researchers conditioned a fear response in adult mice by putting them in a box, where they received shocks every time they heard a certain tone. The mice learned to associate that tone with the painful shock, and when they heard it, they became afraid and froze in their tracks, whether they were being shocked or not. “When we played a tone, they stopped moving, expecting something bad to happen,” says Dr. Stephen Strittmatter, professor of neurology and neuroscience at the Yale School of Medicine and senior author of the study.
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The protein, called beta-catenin, transmits early signals in species ranging from flies to frogs to mice that separate an embryo into front and back or top and bottom. It also acts like Velcro, fastening a cell's internal skeleton to proteins on its external membranes that in turn connect them to other cells.
This is from 2009
University Studies Post Traumatic Stress Disorder and Traumatic Brain Injury
Recently, the University of California, San Diego (UC San Diego) School of Medicine received a $60 million dollar grant for a five-year study to determine better prevention and treatment methods of post traumatic stress disorder (PTSD) and traumatic brain injury (TBI) among American victims and war veterans/soldiers.
The study, which is funded by the Department of Defense Psychological Health/Traumatic Brain Injury Research Program (DoD PH/TBI), will test new therapies to “prevent illness and enhance recovery in individuals at risk for adverse psychological, emotional and cognitive outcomes” caused by TBI and PTSD, according to UC news release.
And then this is from 2009 as well when I put together a list of just how wrong, wrong, wrong and stupid all this is. Note to Pentagon:PTSD? It's only human stupid!
But none of this stopped anyone from getting a lot of money to redo what had been dumped after being paid for as well. I could keep going but you get the point. They actually think that rats grieve? Feel a loss or survival guilt? That they risk their lives everyday for other rats? They still don't understand the basis of PTSD or how to heal it but hey, there's money to be made pretending they can prevent it all again?